2.50
Hdl Handle:
http://hdl.handle.net/10033/621345
Title:
Elsinopirins A-D, Decalin Polyketides from the Ascomycete Elsinoё pyri.
Authors:
Surup, Frank; Pommerehne, Kathrin; Schroers, Hans-Josef; Stadler, Marc ( 0000-0002-7284-8671 )
Abstract:
In course of our screening for new secondary metabolites from ecological niche specialized, phytopathogenic fungi, the plant pathogenElsinoё pyri, strain 2203C, was found to produce four novel compounds (1-4), which were named elsinopirins A-D, in addition to the known metabolite elsinochrome A (5). After isolation by preparative high-performance liquid chromatography (HPLC), their structures, including relative stereochemistry, were elucidated by 1D and 2D nuclear magnetic resonance (NMR) and mass spectrometry (MS) data. Finally, absolute stereochemistry was assigned by chemical shifts of Mosher's esters (α-methoxy-α-trifluoromethylphenylacetic acid; MTPA) derivatives of elsinopirin B (2). The compounds were found to be devoid of significant antibacterial, antifungal, and cytotoxic activities.
Affiliation:
Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Citation:
Elsinopirins A-D, Decalin Polyketides from the Ascomycete Elsinoё pyri. 2018, 8 (1) Biomolecules
Journal:
Biomolecules
Issue Date:
5-Feb-2018
URI:
http://hdl.handle.net/10033/621345
DOI:
10.3390/biom8010008
PubMed ID:
29401753
Type:
Article
Language:
en
ISSN:
2218-273X
Appears in Collections:
publications of the department of microbial drugs (MWIS)

Full metadata record

DC FieldValue Language
dc.contributor.authorSurup, Franken
dc.contributor.authorPommerehne, Kathrinen
dc.contributor.authorSchroers, Hans-Josefen
dc.contributor.authorStadler, Marcen
dc.date.accessioned2018-04-11T12:46:25Z-
dc.date.available2018-04-11T12:46:25Z-
dc.date.issued2018-02-05-
dc.identifier.citationElsinopirins A-D, Decalin Polyketides from the Ascomycete Elsinoё pyri. 2018, 8 (1) Biomoleculesen
dc.identifier.issn2218-273X-
dc.identifier.pmid29401753-
dc.identifier.doi10.3390/biom8010008-
dc.identifier.urihttp://hdl.handle.net/10033/621345-
dc.description.abstractIn course of our screening for new secondary metabolites from ecological niche specialized, phytopathogenic fungi, the plant pathogenElsinoё pyri, strain 2203C, was found to produce four novel compounds (1-4), which were named elsinopirins A-D, in addition to the known metabolite elsinochrome A (5). After isolation by preparative high-performance liquid chromatography (HPLC), their structures, including relative stereochemistry, were elucidated by 1D and 2D nuclear magnetic resonance (NMR) and mass spectrometry (MS) data. Finally, absolute stereochemistry was assigned by chemical shifts of Mosher's esters (α-methoxy-α-trifluoromethylphenylacetic acid; MTPA) derivatives of elsinopirin B (2). The compounds were found to be devoid of significant antibacterial, antifungal, and cytotoxic activities.en
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleElsinopirins A-D, Decalin Polyketides from the Ascomycete Elsinoё pyri.en
dc.typeArticleen
dc.contributor.departmentHelmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalBiomoleculesen

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